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Hers Weight Loss Review: My Experience with Their Custom Semaglutide

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DISCLAIMER InfoAffiliate Disclosure 

We earn commission if you buy through our links.

In our review

The bottom line

When I first joined the Weight Loss program by Hers, they offered Oral Med Kits that included medications like metformin, topiramate, bupropion, and naltrexone. Initially, I noticed some progress with a small drop in weight. However, as time went on, my progress plateaued despite adhering to the meal plans and exercise regimen. This was when Hers introduced their compounded GLP-1 injections. Intrigued by the positive reviews, I asked my medical provider to check if I was eligible to switch to Hers’ compounded semaglutide injections.

Switching to the GLP-1 injections, after evaluation by the provider, proved to be transformative. The process was straightforward, with clear instructions and support from Hers. The most significant change was in my appetite control, as I felt satisfied with smaller portions, making it easier to adhere to my diet. Over the subsequent months, my weight loss resumed at a steady pace, and I felt more in control and motivated. The GLP-1 injections provided the extra boost I needed, and I appreciate the options Hers offers. If you’re considering a new approach to weight loss, the GLP-1 injections could be the solution.

DISCLAIMER Info

DISCLAIMER

Compounded products are not FDA-approved. FDA does not evaluate compounded products for safety, effectiveness, or quality.


Not available in all 50 states. Weight Loss by Hers is a holistic program that includes nutrition support, technological tools, and compounded GLP-1s or medication kits including customized compounded medications prescribed based on what your provider determines is medically appropriate and necessary for you. See website for full details, important safety information, and restrictions, including online provider consultation requirements.


Wegovy® (semaglutide) and Ozempic® (semaglutide) are not compounded. Wegovy® is FDA-approved for weight loss. Ozempic® is FDA-approved for type 2 diabetes treatment but may be prescribed off-label for weight loss at a healthcare provider's discretion.

Hers Weight Loss Subscription Offers

4.8 / 5 stars

Hers weight loss review
  • Affordable compounded GLP-1 Injections, included in the pricing with no insurance required.

  • Content and resources to help you monitor progress and develop healthy habits

  • Access to professional guidance anytime, anywhere

My Experience with Weight Loss Program By Hers

Like many women, especially those dealing with menopause, I’ve tried various weight loss methods, including calorie counting and exercise routines. However, hormones significantly impact weight gain for women. This was my struggle until I discovered compounded semaglutide injections through Hers.

These injections were particularly effective in helping me control my portions, which has been the most significant factor in my long-term weight loss. Before, it was challenging to resist overeating during home-cooked meals, baking sessions, and social gatherings with alcohol. But with the semaglutide injections, my appetite decreased noticeably, making it easier to manage my intake. I can confidently say that suppressing the “food noise” was worth it.

That said, drug regimens alone don’t create sustainable habits around food and exercise. I’ve seen people regain weight after stopping medications like Ozempic. Fortunately, Hers provides helpful tips for incorporating physical activity and offers resources on managing food intake, which has been essential for maintaining my progress. Additionally, with a 12-month subscription, the cost starts as low as $199 per month (if paid upfront), and they offer unlimited access to care team, making it a valuable investment for ongoing support and guidance.

Pros

  • Availability of GLP-1 injections and oral medications for weight loss.
  • Flexible subscription plans.
  • Medications included in the price.
  • Unlimited access to healthcare providers for continuous support.
  • Comprehensive in-app educational content on nutrition, exercise, and mental health.
  • Fast home delivery of medications, typically within a week of getting the prescription.

Cons

  • Compounded semaglutide injections are not available in all states.
  • Limited GLP-1s varieties, only semaglutide available. 

Why I Recommend Hers Weight Loss Subscription

What truly sets Hers apart is their flexibility in offering either compounded GLP-1 weekly injections or daily oral medications that target multiple appetite regulators, prescribed on what your provider determines is medically appropriate and necessary for you. Custom oral medication kits could include a combination of metformin, bupropion, topiramate, vitamin B12, and naltrexone Price of oral medication kits start as low as $79 per month with a 5-month subscription, providing an affordable and effective weight loss solution.

One downside of weight loss by Hers program is that it only offers compounded semaglutide and does not provide other GLP-1 medications such as liraglutide or tirzepatide. This limited selection might be a drawback for those who are specifically seeking alternative GLP-1 options or have a preference for other medications.

In addition to their innovative medication regimen, Hers offers several key services that enhance their holistic weight loss program:

A Solution for All

Hers ensures that everyone has access to a weight loss solution, even if compounded semaglutide isn’t suitable for you. They provide other effective options like metformin, bupropion, naltrexone, and topiramate through personalized oral medication kits. For example, metformin, typically used to control blood sugar levels, is prescribed off-label for weight loss and has been shown to curb hunger. This range of medications allows Hers to customize a treatment plan to fit your individual health profile.

Flexible Subscription Options

Hers offers adaptable subscription plans that accommodate your weight loss journey, with choices extending up to 12 months. This long-term commitment is beneficial because, generally speaking, weight loss of about 10.9% takes around 6 months. By providing these longer subscription options, Hers ensures you have sufficient time to experience the benefits of the treatment and make any necessary adjustments for ongoing success.

Beyond the Meds

Hers offers a tailored educational program through their app, designed to complement your weight loss journey. The program features personalized lessons focusing on your eating habits, practical nutritional advice, easy snack and meal ideas, movement guides, mental health support, and tips for better sleep. This well-rounded content ensures you have all the tools and information needed to enhance your weight loss efforts.

Constant Support 

Hers provides unlimited online check-ins with a care team. Whenever you have questions or need support, you can easily reach out for help. This continuous access to professional advice was invaluable throughout my experience.

Adaptable Dosage Plans

As your weight loss journey progresses, your medication dosage may need adjustments. Hers offers unlimited online dosage changes, making it easy to adapt your treatment plan as needed. This feature ensures that your medication remains effective and helps minimize potential side effects.

My Results With Compounded Weight Loss Medications

Embarking on a weight loss journey can be daunting, but with weight loss medications by Hers, I found a supportive and effective solution. From personalized medication plans to continuous professional guidance, my experience with Hers has been transformative. Here’s a detailed look at how these medications impacted my journey and the results I achieved.

I was prescribed Hers Oral Weight Loss Kit #1

I began my weight loss program through Hers with their Kit #1. Based on your survey and intake, you are recommended different kits that essentially offer the same medications but in various dosages and combinations. This flexibility allows you to find the most suitable medication combination for your specific needs and goals or if you experience a side-effect from specific med. 

In Kit #1, I received a combination of Naltrexone + Bupropion (in a single pill), Metformin, Topiramate, and Vitamin B12. 

  • Metformin: This medication helps control blood sugar levels and is prescribed off-label for weight loss. It works by influencing hormones and molecules that affect hunger. Hers recommends a regimen of metformin that starts with taking one 500 mg tablet each morning with food for the first two weeks to reduce feelings of an upset stomach. Afterward, the dosage is increased to one tablet in the morning and one in the evening.

  • Topiramate: Primarily used to treat epilepsy and migraines, this anticonvulsant is prescribed off-label for weight loss. It helps reduce appetite and increase feelings of fullness. Moreover, it is shown to promote weight loss by reducing body fat mass. Studies have shown a mean weight loss of approximately 5% to 7% after 6 to 12 months of taking 100 mg of topiramate daily. I was prescribed 88 mg to be taken with or without food once a day in the morning.

  • Vitamin B12: Vitamin B12 plays a crucial role in red blood cell formation, DNA production, metabolism, and nerve function. It helps your body produce DNA and keeps your nerves and blood cells healthy. Additionally, Vitamin B12 is important for metabolism, the process your body uses to break down foods and fats. Deficiencies in Vitamin B12 have been associated with obesity and overweight, highlighting its importance in maintaining a healthy weight.

  • Naltrexone: Known as an opioid antagonist used to treat opioid and alcohol use disorders, naltrexone is combined with bupropion in the brand-name medication CONTRAVE®, FDA-approved for chronic weight management in adults with a BMI of 30 kg/m² or greater, or 27 kg/m² or greater with at least one weight-related comorbidity. Hers  recommend starting with half a tablet once in the morning during the first week. In the second week, increase the dose to half a tablet in the morning and half a tablet before bed. By the fourth week, the recommended dose is one whole tablet in the morning and one whole tablet before bed.

  • Bupropion: Commonly known by the brand name Wellbutrin, this antidepressant is used to treat adult depression, seasonal affective disorder, and smoking cessation. Bupropion may also offer weight loss support on its own, with studies showing individuals taking 300 mg of brand-name bupropion daily lost 7.2% of their body weight, while those taking 400 mg lost 10.1% of their body weight. Bupropion has been a game-changer for me, significantly improving impulsivity and executive dysfunction. It also helps reduce food noise and the urge to binge eat.

I Requested a Switch to Compounded GLP-1 Injections

After starting with Naltrexone + Bupropion, Metformin, and Topiramate I began to experience some side effects. Extreme thirst, headaches, light-headedness, and stomach problems made it difficult to continue with the daily regimen. Disclaimer: Everyone’s experience with these medications may vary, and not everyone will encounter the same side effects. Additionally, the idea of taking multiple pills every day felt overwhelming. Seeking a more convenient and manageable option, I decided to switch to compounded GLP-1 injections. The once-a-week compounded semaglutide injections not only reduced the frequency of medication intake but also provided a more effective and comfortable solution for my weight loss journey.

Hers provides access to compounded semaglutide, the same active ingredient found in brand-name Ozempic® and Wegovy®, the FDA-approved GLP-1 treatments for weight management in adults with obesity or overweight. This weekly injection not only aids in weight loss but also helps maintain it. 44.2% of individuals lost up to 10% of their weight with semaglutide at 2 years, compared with 6.9% for those receiving a placebo.

Semaglutide mimics GLP-1, a hormone your body naturally produces to regulate appetite and blood sugar levels. By decreasing appetite and slowing stomach emptying, semaglutide helps promote significant weight loss. Approximately one in three adults achieved a 20% weight loss with Wegovy®, the brand-name semaglutide injection.

How to Get Started with Weight Loss Program By Hers

Starting your weight loss journey with Hers is straightforward and tailored to your needs. It all begins with a detailed survey where you provide information about your health, preferences, and past experiences with medications. This survey helps customize your medication kit, ensuring it aligns with your personal requirements.

Once your details are reviewed by a prescriber, they will initiate a chat with you through the app. You’ll receive a few messages to set expectations and discuss your plan. It’s important to note that the prescriber might change your medication kit if they find any contraindications based on your survey. They may also ask clarifying questions, so keep an eye on these messages and respond promptly to avoid delays in getting your prescription.

Be sure to download the Hers app! It provides detailed instructions on how to start the medications slowly to minimize the risk of side effects. The app also offers educational modules and trackers to help you develop healthy habits. If you encounter any issues, you can easily contact your prescriber through the app’s messaging feature.

After approximately one week on your medication, you’ll receive a notification to complete a brief treatment check-in. These check-ins help ensure your safety and monitor your progress. If your treatment isn’t going as expected, your Care Team can adjust your medication or dosage. The process is quick, taking only a few minutes, and is entirely online.

Note that Hers compounded GLP-1 injections are not available in all 50 US states, but the oral medication kits are widely accessible. This makes it easy to find a solution that works for you, no matter where you are.

Side Effects and Safety of Hers Weight Loss Meds

Like any prescription medication, weight loss medications by Hers may cause side effects in some people. These side effects may include:

Compounded semaglutide side effects

Semaglutide side effects may include: 

  • Vomiting
  • Nausea
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Heartburn
  • Burping

Metformin side effects may include: 

  • Nausea
  • Diarrhea
  • Gas
  • Stomach discomfort or indigestion
  • Constipation
  • Low energy or weakness
  • Headache
  • Skin flushing
  • Rash
  • Muscle pain
  • Nail changes

Topiramate side effects may include: 

  • Confusion
  • Difficulty concentrating
  • Memory problems
  • Changes in taste
  • Speech and language problems
  • Blurry or double vision
  • Abnormal tiredness
  • Nervousness or anxiety
  • Dizziness
  • Tingling, prickling, or burning sensations
  • Clumsiness

Vitamin B12 side effects may include: 

  • Nausea 
  • Dizziness
  • Headaches

Naltrexone & bupropion side effects may include: 

  • Nausea
  • Headache
  • Dizziness
  • Vomiting
  • Insomnia
  • Diarrhea
  • Dry mouth

How Does Hers Compare to Other Weight Loss Programs?

When comparing Hers with other weight loss brands like Henry Meds, Mochi, and ReflexMD, several important differentiating factors emerge. Hers stands out with its affordability, offering pricing as low as $79/month (for a 5-month subscription) of oral medications and $199/month (for a 12-month subscription, paid upfront) for compounded GLP-1 injections. This is significantly lower compared to ReflexMD’s $497/month. Hers also includes both medications and unlimited provider support within their price plan, whereas other brands may charge extra for these services. Additionally, Hers offers comprehensive in-app educational content, providing guidance on nutrition, exercise, and mental health, which is a step above the basic support offered by competitors. However, a notable con is that Hers only offers compounded semaglutide injections, whereas Henry Meds includes both semaglutide and tirzepatide options, providing a broader range of treatment choices.

Verdict: Why Try Hers for Weight Loss

Having tried the weight loss program by Hers, I can confidently say it offers a unique and effective approach. Hers provides either compounded GLP-1 injections or oral medication kits, both evaluated by their medical providers. This comprehensive method, targeting multiple appetite regulators, distinguishes Hers from other programs.

With its budget-friendly subscription plans, Hers presents a cost-effective alternative to brand-name options like Ozempic® and Wegovy®. The convenience of an in-depth initial online consultation, followed by unlimited access to providers for ongoing support and dosage adjustments, ensures continuous professional guidance throughout your journey.

Hers also offers extensive educational content, including nutritional advice, meal ideas, movement guides, mental health support, and sleep tips. This holistic approach enhances the effectiveness of their program. My experience with Hers has been positive, and I highly recommend it to anyone seeking a reliable weight loss program.

FAQs

Is compounded semaglutide FDA-approved?

No, compounded semaglutide is not FDA-approved, but it contains the same active ingredient as the FDA-approved medications Ozempic® and Wegovy®.

Yes, customers often see long-term weight loss results, especially when combining the medications with exercise and proper calorie intake. For example, people have shared success stories such as losing 20 lbs in 6 weeks, 10 lbs in 4 weeks, and 8 lbs in a week when following Hers’ holistic approach.

Pricing varies based on the subscription plan. For example, subscribing to Medication Kit 1 for a 3-month supply costs $297.00, which includes Bupropion XL, Metformin XR, and a combination of Naltrexone, Topiramate, and Vitamin B12.

You may be eligible for semaglutide if you have a BMI of 30 or higher, or 27 or higher with at least one weight-related condition.

You may be ineligible if you have a history of certain medical conditions, such as thyroid cancer or severe kidney issues, or if you’re pregnant or breastfeeding.

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Our editorial team is independent and objective. But to sustain our in-depth research without charging readers, we attempt to partner with some of the companies listed on this page, and may receive marketing compensation in exchange for clicks, purchases, and calls from our site. Such compensation can impact the location and order in which such companies appear on this page. All remain subject to change, however, based on our editorial staff’s decisions. Prices are accurate at the time of publication.